Table 4. Interaction analysis between smoking and rs17716310 associated with CRC risk.

Smoking stusus	Genotype	Case/Control	OR (95%CI)a	P mult a	P add
Non-smoker	AA	189/232	1.000	0.013	0.238
	AC+CC	250/257	1.192 (0.919–1.547)
Smoker	AA	104/105	1.281 (0.886–1.853)
	AC+CC	137/103	1.712 (1.196–2.451)

P _mult was calculated using the multiplicative interaction term.

P _add was calculated using the additive interaction model.

^a Data were calculated by logistic regression model after adjusting for gender and age group.

The nominal significant results were in bold.