Fig 2. The anesthetics sodium pentobarbital and ketamine/xylazine do not increase host susceptibility to Lm intravenous infection.

Mice were intravenously infected with a low sublethal dose of 2 x 10³ CFU Lm together with intravenous injection of vehicle solution, propofol, pentobarbital, or alternatively infection was carried out 24 hours after sedation with ketamine/xylazine to avoid direct toxic effects of the drug on bacteria. Graph depicts bacterial burdens in the liver at three days post-infection. ‘X’ indicates animals with bacterial burdens that were below detection limits. Data shown is combined from two independent experiments, error bars indicate data ± SEM. * p<0.05, *** p<0.0005