Table 3. Multivariate analysis for evaluating prognostic factors influencing outcomes.

	OS		DFS		LRRFS		DMFS
	p	HR (95% CI)	p	HR (95% CI)	p	HR (95% CI)	p	HR (95% CI)
LNR (>0.152)	0.041	2.17 (1.03–4.57)	0.005	2.28 (1.28–4.07)		–	0.010	2.30 (1.23–4.32)
Perineural invasion	0.002	2.96 (1.47–5.93)	<0.001	3.09 (1.75–5.46)	0.027	3.60 (1.15–11.24)	0.001	2.82 (1.51–5.25)
Type of surgery (APR)	0.004	3.91 (1.56–9.81)		–		–		–
TRG (3–4)	0.080	0.16 (0.02–1.24)		–		–		–
Pre-NCRT CEA level (>5 ng/mL)		–	0.073	1.70 (0.95–3.02)		–		–

HR, hazard ratio; CI, confidence interval. Other abbreviations as in Tables 1 and 2.