Table 4. Previously reported lymph node ratio studies of rectal cancer patients who underwent preoperative chemoradiotherapy.

Author	Study years	No.	Proportion of preoperative CRT (%)	Proportion of adjuvant chemotherapy (%)	Median follow-up (months)	Median/mean examined LNs (range)	Median/mean positive LNs (range)	Cut-off value of LNR	Outcomes significantly associated with LNR
Kang et al.12	1990–2006	75	100	100	35	18 (5–80)	2 (1–79)	0.143	OS
Klos et al.8	1998–2008	281	100	67	42	12	NR	0.09 and 0.36	CSS
Lee et al.9	2001–2007	154	100	100	52	15 (3–46)	NR	0.15 and 0.3	OS and DFS
Nadoshan et al.11	1996–2007	128	100	49	39	10 (2–28)	6 (1–25)	0.2	OS, LRRFS, and DMFS
Madbouly et al.10	2006–2010	115	100	100	37	12 (5–25)	4 (1–19)	0.375	OS and DFS
Present study	2004–2011	125	100	100	55	17 (1–50)	2 (1–17)	0.152	OS, DFS, and DMFS

NR, not reported; CSS, cancer-specific survival. Other abbreviations as in Tables 1 and 2.