Table 1. Subject Characteristics.
Subject Group | NMO | MS | Control |
---|---|---|---|
Number attending baseline | 18 | 15 | 17 |
Age, Range (median) | 20–76 (46) | 22–62 (38) | 21–77 (47) |
Sex | 15F, 3M | 11F, 4M | 13F, 4M |
Aquaporin-4 antibody positive | 18 | 0 | 0 |
EDSS, range (median) | 2–6 (4) | 0–5 (2) | - |
Disease Duration, range (median) | 12–186 (57.5) | 24–240 (72) | - |
Number Attending Follow-up at 1 year | 16 | 13 | 16 |
Age attending follow-up, range (median) | 20–76 (46) | 29–62 (40) | 21–77 (47) |
Number of days to follow-up, range (median) | 350–456 (386) | 346–420 (378) | 340–430 (372) |
Immunomodulation | Aza 9, Mtx 2, Pred 1, Aza+Pred 3, Mtx+Pred 3 | Inf 3, Glt 6, None 6 | - |
Number with brain lesions at baseline MRI | 13 | 15 | - |
Number with cervical spinal cord lesion at baseline MRI | 14 | 10 | - |
Number with severe visual impairment (VA ≤ 0.1). | 9 (4 of which had bilateral severe visual impairment) | 0 | - |
Abbreviations:
Aza: Azathioprine
Glt: Glatiramer
Inf: β-Interferon
Mtx: Methotrexate
MS: Multiple sclerosis
NMO: Neuromyelitis optica
Pred: Prednisolone
VA: Visual Acuity.