Table 1. Main statistical results corresponding to behavioral tests.

	%internal ambulation (OF)		Total ambulation (OF)		Rearing frequency (OF)		DI (NOT)		Exploration 30 s (NOT)		%open arms entries (EPM)		Closed arms entries (EPM)
	F1,83	p-value	F1,83	p-value	F1,83	p-value	F1,78	p-value	F1,78	p-value	F1,25	p-value	F1,25	p-value
Litter	9.29	<0.005	0.22	ns	4.09	<0.05	4.62	<0.05	4.88	<0.05	0.20	ns	8.03	<0.01
Sex	6.01	<0.05	15.21	<0.005	37.95	<0.005	8.78	<0.01	0.09	ns	-	-	-	-
MD	12.70	<0.005	0.31	ns	4.80	<0.05	3.48	ns	0.73	ns	0.19	ns	0.50	ns
Leptin	5.67	<0.05	0.23	ns	1.33	ns	0.40	ns	0.59	ns	2.61	ns	1.89	ns
Sex x MD	0.31	<0.05	0.05	ns	1.06	ns	0.04	ns	4.41	<0.05	-	-	-	-
Sex x Leptin	0.27	ns	0.67	ns	0.50	ns	0.27	ns	0.03	ns	-	-	-	-
MD x Leptin	0.31	ns	8.34	<0.01	9.47	<0.005	0.53	ns	0.32	ns	0.94	ns	0.65	ns
Sex x MD x Leptin	1.97	ns	0.01	ns	0.01	ns	1.35	ns	0.71	ns	-	-	-	-

Main significant results extracted from the three-way ANCOVA (litter was considered as a covariate factor). See material and methods section for details.