Table 2. Bone structural parameters for femur and 3rd lumbar vertebra from 30 week old mice.
| Males | Females | |||||||
|---|---|---|---|---|---|---|---|---|
| C/C | HF/C | C/HF | HF/HF | C/C | HF/C | C/HF | HF/HF | |
| (n = 5) | (n = 6) | (n = 5) | (n = 7) | (n = 5) | (n = 6) | (n = 6) | (n = 7) | |
| Femur | Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) |
| BvTv | 27.1 (2.3)a | 22.3 (10.0)ab | 20.5 (4.2)ab | 13.5 (4.2)b | 4.2 (1.4) | 6.0 (1.2) | 5.9 (1.8) | 5.1 (0.7) |
| BsBv | 36.9 (2.1) | 38.4 (11.7) | 37.8 (6.3) | 38.8 (5.0) | 55.3 (4.0)a | 49.2 (2.8)ab | 45.7 (4.9)b | 47.3 (3.5)b |
| TbTh / mm | 0.099 (0.006) | 0.106 (0.021) | 0.102 (0.013) | 0.103 (0.012) | 0.079 (0.004) | 0.085 (0.005) | 0.091 (0.009) | 0.091 (0.008) |
| TbSp / mm | 0.200 (0.017)a | 0.282 (0.033)b | 0.264 (0.040)ab | 0.381 (0.049)c | 0.437 (0.039) | 0.425 (0.044) | 0.477 (0.043) | 0.461 (0.069) |
| SMI | 1.6 (0.1)a | 2.1 (0.5)ab | 2.0 (0.3)ab | 2.4 (0.2)b | 2.9 (0.2) | 2.7 (0.1) | 2.8 (0.3) | 2.8 (0.1) |
| TbPF / mm-1 | 4.9 (1.3)a | 12.2 (8.2)ab | 9.9 (3.7)ab | 13.9 (3.8)b | 26.7 (3.9)a | 21.7 (1.8)b | 20.2 (2.1)b | 23.0 (2.4)ab |
| Vertebra | ||||||||
| BvTv | 43.7 (3.3)a | 28.9 (1.9)b | 40.1 (11.5)ab | 36.0 (3.8)ab | 25.6 (3.0)a | 31.1 (6.7)ab | 35.3 (1.4)b | 31.5 (3.1)ab |
| BsBv | 35.6 (2.1)a | 42.7 (2.7)a | 35.2 (5.8)a | 36.5 (3.2)a | 41.2 (2.3)a | 37.0 (2.3)b | 31.3 (0.6)c | 34.4 (1.2)b |
| TbTh / mm | 0.093 (0.004)a | 0.083 (0.006)a | 0.097 (0.011)a | 0.092 (0.008)a | 0.086 (0.003)a | 0.092 (0.005)a | 0.108 (0.003)b | 0.099 (0.003)c |
| TbSp / mm | 0.148 (0.009)a | 0.183 (0.009)b | 0.168 (0.030)ab | 0.177 (0.007)b | 0.300 (0.023)a | 0.246 (0.051)a | 0.250 (0.012)a | 0.251 (0.027)a |
| SMI | 0.8 (0.2)a | 1.6 (0.1)b | 1.1 (0.7)ab | 1.2 (0.2)ab | 1.6 (0.2)a | 1.2 (0.4)a | 1.2 (0.2)a | 1.3 (0.1)a |
| TbPF / mm-1 | -0.7 (1.9)a | 8.0 (0.9)b | 1.8 (6.0)ab | 3.4 (2.0)ab | 7.3 (1.8)a | 3.9 (0.4)ab | 3.3 (1.1)b | 4.4 (1.0)ab |
Abbreviations are BvTv: trabecular bone volume to total volume, BsBv: Bone surface to bone volume ratio, TbTh: Trabecular thickness, TbSp: Trabecular spacing, SMI: Structural model index, TbPF: Trabecular pattern factor. a, b,c: For each parameter measured, values with different superscript letters are significantly different from each other (p<0.05) within the same sex.