. 2015 Sep 18;10(9):e0138730. doi: 10.1371/journal.pone.0138730

Table 3. Linear regression analysis between femoral vitamin K-dependent protein expression levels and bone structural factors of the femur or 3^rd lumbar vertebra.

A. Males
Site	Factor	Mgp			Osteocalcin			Gas6			Periostin			Ggcx			Vkor
		β	r²	p	β	r²	p	β	r²	p	β	r²	p	β	r²	p	β	r²	p
Femur	Bone volume	-0.23	0.06	ns	-0.03	0.00	ns	-0.28	0.08	ns	-0.16	0.02	ns	-0.25	0.06	ns	-0.11	0.01	ns
	Length	-0.18	0.03	ns	-0.13	0.02	ns	-0.12	0.02	ns	-0.44	0.19	0.06	-0.30	0.09	ns	-0.18	0.03	ns
	BvTv	-0.34	0.12	ns	-0.29	0.08	ns	0.36	0.13	ns	-0.43	0.18	0.07	-0.56	0.31	0.007	-0.55	0.30	0.007
	BsBv	0.04	0.00	ns	0.03	0.00	ns	-0.03	0.00	ns	0.01	0.00	ns	0.17	0.03	ns	0.08	0.01	ns
	TbTh	-0.02	0.00	ns	-0.11	0.01	ns	-0.22	0.05	ns	-0.03	0.00	ns	-0.20	0.04	ns	-0.02	0.00	ns
	TbSp	0.53	0.29	0.02	0.44	0.19	0.05	-0.50	0.25	0.02	0.58	0.34	0.009	0.64	0.40	0.001	0.63	0.40	0.001
	SMI	0.29	0.09	ns	0.11	0.01	ns	-0.53	0.29	0.01	0.23	0.05	ns	0.38	0.15	0.08	0.47	0.22	0.02
	TbPF	0.20	0.04	ns	0.07	0.00	ns	-0.45	0.20	0.04	0.11	0.01	ns	0.32	0.10	ns	0.33	0.11	ns
	MidWT	-0.39	0.15	ns	-0.16	0.03	ns	-0.16	0.03	ns	-0.10	0.01	ns	-0.13	0.02	ns	-0.12	0.02	ns
	MidD	0.00	0.00	ns	0.02	0.00	ns	-0.40	0.16	0.08	0.02	0.00	ns	0.11	0.01	ns	0.16	0.02	ns
	Multivariant	F(10,4) = 3.57		ns	F(10,4) = 1.16		ns	F(10,7) = 2.32		ns	F(10,4) = 9.71		0.02	F(10,6) = 1.28		ns	F(10,7) = 2.55		ns
	+ Maternal diet	F(11,3) = 2.43		ns	F(11,3) = 1.15		ns	F(11,6) = 1.88		ns	F(11,3) = 6.74		0.07	F(11,5) = 1.08		ns	F(11,6) = 2.16		ns
	+ Offspring diet	F(11,3) = 2.52		ns	F(11,3) = 0.90		ns	F(11,6) = 2.30		ns	F(11,3) = 11.99		0.03	F(11,5) = 1.83		ns	F(11,6) = 3.39		0.07
Vertebra	Length	0.13	0.02	ns	-0.04	0.00	ns	-0.30	0.09	ns	-0.14	0.02	ns	0.02	0.00	ns	0.32	0.10	ns
	BvTv	-0.16	0.03	ns	-0.04	0.00	ns	0.39	0.16	ns	0.07	0.01	ns	-0.00	0.00	ns	0.03	0.00	ns
	BsBv	0.05	0.00	ns	-0.01	0.00	ns	-0.16	0.03	ns	-0.13	0.02	ns	-0.14	0.02	ns	-0.27	0.07	ns
	TbTh	-0.14	0.02	ns	-0.15	0.02	ns	0.01	0.00	ns	-0.08	0.01	ns	0.03	0.00	ns	0.20	0.04	ns
	TbSp	0.24	0.06	ns	0.05	0.00	ns	-0.55	0.31	0.01	-0.01	0.00	ns	0.09	0.01	ns	0.20	0.04	ns
B. Females
Site	Factor	Mgp			Osteocalcin			Gas6			Periostin			Ggcx			Vkor
		β	r²	p	β	r²	p	β	r²	p	β	r²	p	β	r²	p	β	r²	p
Femur	Bone volume	-0.12	0.02	ns	0.44	0.19	0.05	-0.18	0.03	ns	-0.43	0.18	ns	0.07	0.01	ns	0.46	0.21	0.06
	Length	-0.27	0.07	ns	0.36	0.13	ns	0.01	0.00	ns	0.34	0.11	ns	0.05	0.00	ns	0.13	0.02	ns
	BvTv	0.03	0.00	ns	0.40	0.16	0.08	-0.31	0.09	ns	-0.20	0.04	ns	-0.03	0.00	ns	0.18	0.03	ns
	BsBv	-0.17	0.03	ns	-0.52	0.28	0.02	0.29	0.08	ns	0.39	0.15	ns	-0.14	0.02	ns	-0.38	0.14	ns
	TbTh	0.19	0.04	ns	0.43	0.18	0.05	-0.14	0.02	ns	-0.31	0.09	ns	0.20	0.04	ns	0.29	0.09	ns
	TbSp	0.01	0.00	ns	-0.21	0.04	ns	0.03	0.00	ns	-0.53	0.28	0.02	-0.22	0.05	ns	-0.04	0.00	ns
	SMI	0.05	0.00	ns	-0.23	0.05	ns	0.15	0.02	ns	0.21	0.04	ns	0.32	0.10	ns	-0.19	0.04	ns
	TbPF	0.00	0.00	ns	-0.37	0.14	ns	0.39	0.16	ns	0.48	0.23	0.03	0.09	0.01	ns	-0.24	0.06	ns
	MidWT	-0.45	0.20	0.06	0.05	0.00	ns	-0.49	0.24	0.03	-0.42	0.18	ns	-0.47	0.22	0.03	-0.10	0.01	ns
	MidD	0.50	0.25	0.03	0.58	0.34	0.006	0.13	0.02	ns	-0.22	0.05	ns	0.54	0.29	0.009	0.77	0.59	<0.001
	Multivariant	F(10,4) = 0.82		ns	F(10,7) = 0.85		ns	F(10,6) = 0.64		ns	F(10,4) = 1.08		ns	F(10,7) = 2.29		ns	F(10,5) = 1.57		ns
	+ Maternal diet	F(11,3) = 0.68		ns	F(11,6) = 1.71		ns	F(11,5) = 1.49		ns	F(11,3) = 1.72		ns	F(11,6) = 1.78		ns	F(11,4) = 1.42		ns
	+ Offspring diet	F(11,3) = 1.41		ns	F(11,6) = 2.18		ns	F(11,5) = 0.83		ns	F(11,3) = 0.74		ns	F(11,6) = 2.59		ns	F(11,4) = 1.15		ns
Vertebra	Length	0.04	0.00	ns	0.33	0.11	ns	0.28	0.08	ns	-0.22	0.05	ns	0.27	0.08	ns	0.35	0.12	ns
	BvTv	0.31	0.10	ns	0.27	0.07	ns	-0.20	0.04	ns	-0.59	0.35	0.02	0.09	0.01	ns	0.32	0.11	ns
	BsBv	-0.38	0.15	ns	-0.52	0.27	0.02	0.09	0.01	ns	0.71	0.51	0.002	-0.15	0.02	ns	-0.46	0.21	0.07
	TbTh	0.34	0.11	ns	0.50	0.25	0.03	-0.08	0.01	ns	-0.77	0.59	<0.001	0.05	0.00	ns	0.44	0.19	0.08
	TbSp	-0.23	0.06	ns	-0.06	0.00	ns	0.30	0.09	ns	0.32	0.10	ns	-0.19	0.04	ns	-0.36	0.13	ns

Abbreviations are BvTv: trabecular bone volume to total volume, BsBv: Bone surface to bone volume ratio, TbTh: Trabecular thickness, TbSp: Trabecular spacing, SMI: Structural model index, TbPF: Trabecular pattern factor, MidWT: Midshaft wall thickness, MidD: Midshaft diameter. For Diet, β value is based on high fat diet having a higher value than control diet.

Table 3. Linear regression analysis between femoral vitamin K-dependent protein expression levels and bone structural factors of the femur or 3rd lumbar vertebra.

Table 3. Linear regression analysis between femoral vitamin K-dependent protein expression levels and bone structural factors of the femur or 3^rd lumbar vertebra.