Table 3.

Microarray data of axonal miRNAs altered by axonal application of sildenafil and CSPGs.

Down-regulated miRNAs	Average CT (±SD)	Fold changes vs CSPGs only	p-value
miR-19a-3p	29.4±0.1	−3.0	0.001
miR-29c-3p	30.7±0.1	−2.5	0.019
miR-20b-5p	27.7±0.0	−2.4	0.001
miR-489-3p	34.2±0.2	−2.4	0.013
miR-9a-3p	24.0±0.0	−2.3	0.001
miR-19b-3p	29.3±0.0	−2.3	0.001
miR-20a-5p	26.4±0.0	−2.3	0.011
miR-29a-3p	31.4±0.2	−2.2	0.024
miR-376b-3p	30.2±0.3	−2.1	0.016
miR-30e-5p	26.8±0.0	−2.1	0.001
miR-195-5p	27.9±0.2	−2.1	0.009
miR-128-3p	24.9±0.1	−2.0	0.000
miR-125b-5p	23.1±0.0	−2.0	0.004
miR-338-3p	32.1±0.5	−1.9	0.013
miR-30d-5p	26.8±0.0	−1.8	0.000
miR-30a-5p	26.3±0.1	−1.8	0.003
miR-148b-3p	29.5±0.2	−1.7	0.020
miR-146b-5p	32.0±0.9	−1.7	0.358
miR-22-3p	28.8±0.2	−1.7	0.075
miR-15b-5p	27.9±0.1	−1.7	0.072
miR-140-5p	31.3±0.2	−1.6	0.042
miR-130a-3p	28.7±0.0	−1.6	0.001
miR-9a-5p	21.8±0.1	−1.5	0.011
miR-24-3p	27.5±0.1	−1.5	0.004
miR-337-3p	33.1±0.5	−1.5	0.322
miR-93-5p	27.9±0.2	−1.5	0.063
Up-regulated miRNAs	Average CT (±SD)	Fold changes vs CSPGs only	p-value
miR-105	29.1±0.0	9.0	0.000
miR-511-5p	28.9±0.1	5.5	0.004
miR-133b-3p	32.5±0.2	4.5	0.027
miR-298-5p	26.8±0.0	4.3	0.002
miR-339-5p	29.4±0.3	3.7	0.042
miR-146a-5p	29.7±0.0	3.7	0.000
miR-346	28.7±0.1	2.9	0.010
miR-488-3p	30.5±0.1	2.9	0.028
miR-150-5p	31.7±0.2	2.8	0.326
miR-381-3p	29.4±0.1	2.7	0.017
miR-431	29.0±0.2	2.5	0.060
miR-33-5p	33.4±0.5	2.4	0.148
miR-484	27.6±0.2	2.4	0.023
miR-34a-5p	31.0±0.1	2.4	0.011
miR-203a-3p	32.4±0.0	2.3	0.057
miR-92b-3p	24.9±0.0	2.3	0.043
let-7b-5p	24.5±0.0	2.1	0.004
miR-212-3p	30.3±0.4	2.1	0.125
miR-181d-5p	26.9±0.1	2.0	0.010
miR-29b-3p	33.0±0.4	2.0	0.202
miR-361-5p	30.1±0.1	1.9	0.063
miR-181a-5p	26.7±0.1	1.6	0.010
miR-433-3p	28.2±0.1	1.5	0.046
miR-151-3p	28.7±0.2	1.5	0.114

Data are mean ± SD. n=4/group.