Table 2.

Baseline demographics, comorbidities, and medical history

Characteristic	Germany (N = 599)	Austria (N = 300)	Greece (N = 300)	Belgium (N = 301)
Age, years, mean (SD)	72.4 (8.6)	71.0 (9.5)	66.4 (9.3)	71.2 (10.4)
Age at menopause, years, mean (SD)	48 (5.8)	49.4 (5.8)	47.7 (5.3)	49.4 (4.7)
Time since PMO diagnosis, years, mean (SD)	6.0 (5.6)	6.5 (6.5)	6.4 (6.3)	6.4 (8.2)
Smoking, n (%)
Never	427 (71.3)	212 (70.7)	228 (76.0)	236 (78.4)
Formerly	52 (8.7)	40 (13.3)	24 (8.0)	32 (10.6)
Currently	50 (8.3)	48 (16.0)	47 (15.7)	33 (11.0)
Missing	70 (11.7)	0 (0.0)	1 (0.3)	0 (0.0)
Prior osteoporotic fracture, n (%)	372 (62.1)	122 (40.7)	92 (30.7)	151 (50.2)
Vertebral	182 (30.4)	28 (9.3)	34 (11.3)	51 (16.9)
Non-vertebral	260 (43.4)	101 (33.7)	65 (21.7)	126 (41.9)
Parental history of hip fracture, n (%)
Yes	54 (9.0)	34 (11.3)	52 (17.3)	29 (9.6)
No	272 (45.4)	197 (65.7)	192 (64.0)	188 (62.5)
Unknown	273 (45.6)	69 (23.0)	55 (18.3)	84 (27.9)
Missing	0 (0.0)	0 (0.0)	1 (0.3)	0 (0.0)
Prior PMO therapy, n (%)	532 (88.8)	252 (84.0)	244 (81.3)	256 (85.0)
Baseline T-scores, mean (SD)
Total hip	−2.0 (0.8)	−2.0 (0.8)	−2.0 (0.9)	−2.1 (0.9)
Femoral neck	−2.3 (0.8)	−2.2 (0.8)	−2.6 (0.8)	−2.5 (0.7)
Lumbar spine	−2.7 (1.1)	−2.8 (0.9)	−2.7 (0.8)	−2.2 (1.3)
MMAS-8a
Total adherence score, mean (SD)	7.0 (1.2)	6.6 (1.5)	6.2 (1.8)	7.1 (1.6)
Low or medium adherence score, n (%)	266 (57.6)	177 (67.0)	187 (74.8)	113 (37.5)

MMAS-8 Morisky 8-Item Medication Adherence Scale, PMO postmenopausal osteoporosis, SD standard deviation

^aScores calculated from women who answered all questions in the MMAS-8 questionnaire. Scores ranged from 0 to 8, with high adherence represented by a score of 8, medium adherence by a score of 6–7, and low adherence by a score of less than 6