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. 2015 Sep 18;12:19. doi: 10.1186/s12976-015-0011-4

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© Rodríguez et al. 2015

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — FA cells arrest at G2 phase in response to MMC. a Flow cytometry analysis showing accumulation of FA cells in G2 in response to MMC (left panel) and diminished number of FA mitotic cells compared to normal cells (right panel). b FA cells activate CHK1 kinase in response to MMC treatment. c FA cells increase the expression of p21 mRNA as showed by qRT-PCR analysis (n = 3 independent experiments, p < 0.05)