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. 2015 Sep 18;22(1):77. doi: 10.1186/s12929-015-0185-4

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© Dai et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Immunofluorescence and quantification of cells exhibiting 5 or more FANCD2 foci in lung cancer cells. Cisplatin-induced FANCD2 foci formation in A549 (a) and A549/DDP cells (b) were inhibited markedly by knockdown of FANCF, FANCL, and FANCD2. c The graph below show quantified data of FANCD2 foci in the two cells. cisplatin-induced FANCD2 foci expressions were stronger in A549/DDP than in A549 cells