Boxplot of partial brain oxygen tension versus time in the intervention group. PbtO2, partial brain oxygen tension; Time 0, prerandomization; Time 1, first hour of hypothermia (<35°C); Time 2, first episode of stable hypothermia (<35°C); Time 3, 6 hours of hypothermia (<35°C). Mean decrease in PbtO2 from Time 0 to Time 2 of 7.8±3.1 mmHg (p<0.05) from 30.2 to 22.4 mmHg.