Table 2.
Association of Caffeine Intake During the Epidemiology of Diabetes Interventions and Complications Study with Skin Intrinsic Fluorescence
| SIF outcome (excitation wavelength), model | Variance | β±SE | P value |
|---|---|---|---|
| SIF1 (375 nm)kx=0.6, km=0.2a | |||
| Unadjusted (M1) | 11.2% | 0.000321±2.63E-05 | 2.28×10−32 |
| Adjusted (M2) | 3.8% | 0.000203±2.43E-05 | 1.66×10−16 |
| SIF14 (456 nm)kx=0.4, km=0.8a | |||
| Unadjusted (M1) | 10.7% | 0.000356±3E-05 | 7.19×10−31 |
| Adjusted (M2) | 4.2% | 0.000244±2.98E-05 | 7.19×10−16 |
The value of β±SE was obtained from linear regression (n=1,181). Variance was calculated as a type II squared semipartial correlation. Adjusted models included age, sex, skin tone, clinic latitude, smoking status, any estimated glomerular filtration rate of <60 mL/min/1.73 m2, Diabetes Control and Complications Trial eligibility hemoglobinA1c, mean Diabetes Control and Complications Trial hemoglobin A1c, and mean Epidemiology of Diabetes Interventions and Complications hemoglobin A1c as covariates.
a
Ln transformed.
M1, Model 1; M2, Model 2; SIF, skin intrinsic fluorescence.