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. 2015 Oct 1;17(10):726–734. doi: 10.1089/dia.2015.0017

Table 3.

Association of rs1495741 and Caffeine Intake During the Epidemiology of Diabetes Interventions and Complications Study with Skin Intrinsic Fluorescence

SIF outcome (excitation wavelength), predictor Variance β±SE P value
SIF1 (375 nm)kx=0.6, km=0.2a
 rs1495741 2.9% −0.0596±0.008 4.24E-13
 Caffeine 3.8% 0.000203±2.42E-05 1.93E-16
SIF14 (456 nm)kx=0.4, km=0.8a
 rs1495741 9.7% −0.12265±0.009 2.98E-36
 Caffeine 4.3% 0.000245±2.8E-05 7.86E-18

Data shown are β±SE from linear regression models including both rs1495741 and caffeine intake during Epidemiology of Diabetes Interventions and Complications effects with SIF1LED 375 nm[0.6,0.2] and SIF14LED 456 nm[0.4, 0.8], after adjusting for age, sex, skin tone, clinic latitude, smoking status, any estimated glomerular filtration rate of <60 mL/min/1.73 m2, Diabetes Control and Complications Trial eligibility hemoglobin A1c, mean Diabetes Control and Complications Trial hemoglobin A1c, and mean Epidemiology of Diabetes Interventions and Complications hemoglobin A1c (n=1,077). Variance was calculated as a type II squared semipartial correlation.

a

Ln transformed.

LED, light-emitting diode; SIF, skin intrinsic fluorescence.