Table 3.
Association of rs1495741 and Caffeine Intake During the Epidemiology of Diabetes Interventions and Complications Study with Skin Intrinsic Fluorescence
| SIF outcome (excitation wavelength), predictor | Variance | β±SE | P value |
|---|---|---|---|
| SIF1 (375 nm)kx=0.6, km=0.2a | |||
| rs1495741 | 2.9% | −0.0596±0.008 | 4.24E-13 |
| Caffeine | 3.8% | 0.000203±2.42E-05 | 1.93E-16 |
| SIF14 (456 nm)kx=0.4, km=0.8a | |||
| rs1495741 | 9.7% | −0.12265±0.009 | 2.98E-36 |
| Caffeine | 4.3% | 0.000245±2.8E-05 | 7.86E-18 |
Data shown are β±SE from linear regression models including both rs1495741 and caffeine intake during Epidemiology of Diabetes Interventions and Complications effects with SIF1LED 375 nm[0.6,0.2] and SIF14LED 456 nm[0.4, 0.8], after adjusting for age, sex, skin tone, clinic latitude, smoking status, any estimated glomerular filtration rate of <60 mL/min/1.73 m2, Diabetes Control and Complications Trial eligibility hemoglobin A1c, mean Diabetes Control and Complications Trial hemoglobin A1c, and mean Epidemiology of Diabetes Interventions and Complications hemoglobin A1c (n=1,077). Variance was calculated as a type II squared semipartial correlation.
Ln transformed.
LED, light-emitting diode; SIF, skin intrinsic fluorescence.