FIG. 1.

Density-derived feature measurement in motor network. Motor network reconstruction (step 1). Extraction of GFA/MTR density-derived features along the M1-SMA intrahemispheric connection. Yellow arrows indicate the regions of interest (step 2). On the right, GFA/MTR histograms of M1-SMA for each control (N=10) at tp1 and tp2; comparison of density-derived features between controls and patients at tp1–tp2. Each line is representing the significance of the p-value for each density-derived feature in each connection (intra- or interhemispheric). CC-m, corpus callosum-midline; GFA, generalized fractional anisotropy; M1, primary motor area; MTR, magnetization transfer ratio; PMd, premotor dorsal area; PMv, premotor ventral area; ROI, region of interest; N, total number of subjects; SC, somatosensory cortex; SMA, supplementary motor area.