Table 2.
Laboratory results and amino acid concentrations
| Cachectic patients (n = 8) | Control Patients (n = 7) | P-value | |
|---|---|---|---|
| CRP (mg/L) | 8.3 (4.2–31.3) | 0 (0–1.8) | 0.002 |
| WBC (*109/L) | 8.4 (4.6–10.5) | 7.1 (4.9–8.3) | 0.431 |
| Bilirubin (µmol/L) | 10.0 (8.0–18.0) | 10.5 (7.8–18.5) | 0.943 |
| ALT (IU/L) | 36.0 (34.0–67.0) | 20.5 (14.5–30.8) | 0.015 |
| GGT (IU/L) | 93.0 (47.0–168.0) | 21.0 (15.8–30.5) | 0.010 |
| ALP (IU/L) | 214.0 (149.0–231.0) | 67.5 (60.3–101.5) | 0.007 |
| Urea (mmol/L) | 4.9 (3.5–6.3) | 5.2 (5.0–7.7) | 0.391 |
| Creatinine (µmol/L) | 81.0 (74.0–101.0) | 92.0 (82.5–106.3) | 0.199 |
| Phenylalanine (fasted, µmol/L) | 44.5 (41.3–60.5) | 67.0 (59.0–71.0) | 0.024 |
| Phenylalanine (fed, µmol/L) | 62.5 (56.3–69.5) | 84.0 (70.0–96.0) | 0.009 |
| Tyrosine (fasted, µmol/L) | 50.0 (41.8–65.0) | 53.0 (45.0–59.0) | 0.817 |
| Tyrosine (fed, µmol/L) | 64.0 (45.0–75.0) | 74.0 (55.0–90.0) | 0.246 |
| Valine (fasted, µmol/L) | 124.5 (109.3–154.5) | 204.0 (179.0–220.0) | 0.005 |
| Valine (fed, µmol/L) | 162.0 (143.3–176.0) | 252.0 (223.0–281.0) | 0.001 |
Laboratory results and amino acid concentrations are presented as median and interquartile range. Amino acid concentrations are given as average concentrations in the fasted (1–4 h) and fed state (5–8 h). All amino acid concentrations increased significantly (P < 0.05) during feeding except for Tyrosine in the cachexia group (P = 0.062).
ALP, alkaline phosphatase; ALT, alanine transaminase; CRP, C-reactive protein; GGT, gamma-glutamyl transferase; WBC, white blood cells