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gAd improves vascular response to insulin in HFD rats via AMPK-mediated pathway
Each rat was fed with either a HFD or LFD for 4 weeks. The distal saphenous artery was isolated, pre-constricted with phenylephrine (PE) and the vasodilatory responses to gAd (A and B) or insulin (C and D) with or without the pretreatment with gAd (1 μg ml−1) and/or Compound C (5 μm) were determined. *P < 0.05 compared with HFD control (ANOVA). #P < 0.05 compared with gAd + HFD. n = 6 each.
