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gAd restores endothelial responses to ACh in HFD rats
Each rat was fed either a HFD or LFD for 4 weeks. The distal saphenous artery was isolated, pre-constricted with phenylephrine, and the vasodilatory responses to ACh (A) in the presence or absence of gAd and/or Compound C, or sodium nitroprusside (SNP) (B) were determined. *P < 0.05 compared with LFD control (ANOVA). #P < 0.05 compared with HFD + gAd. n = 4–6 each.
