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. Author manuscript; available in PMC: 2016 Jul 1.
Published in final edited form as: Prostaglandins Other Lipid Mediat. 2015 Mar 23;120:9–16. doi: 10.1016/j.prostaglandins.2015.03.002

Table 1.

Summary of CYP450 ω-hydroxylases that produce 20-HETE in humans, rats, and mice.

Species Cytochrome P450 ω-hydroxylases responsible for 20-HETE production
Human CYP4A11 (CYP4A11); CYP4A22 (CYP4A22); CYP4F2 (CYP4F2); CYP4F3 (CYP4F3)
Rat Cyp4a1 (CYP4A1); Cyp4a2 (CYP4A2); Cyp4a3 (CYP4A3); Cyp4a8 (CYP4A8)
Mouse Cyp4a10 (CYP4A10); Cyp4a12 (CYP4A12)

gene; (protein)