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. Author manuscript; available in PMC: 2016 Sep 18.
Published in final edited form as: ACS Chem Biol. 2015 Jun 23;10(9):2048–2056. doi: 10.1021/acschembio.5b00244

Figure 3.

Figure 3

Structure of CalS13 in complex with PLP (internal aldimine form) and keto-substrate TDP-4-keto-4,6-dideoxy-α-d-glucose (top panel) and WecE in complex with PLP (external aldimine form) and amino-product TDP-4-amino-4,6-dideoxy-α-d-galactose (bottom panel). (A) Homodimer structure where the C-terminal “small” domain is colored blue in two monomers (green and yellow) and the arrow indicates the distance between two active sites of the homodimer assembly. (B) Monomeric structure where N-terminal “large” and C-terminal “small” domains are colored yellow and blue, respectively.