Fig. 1.

Increase in mean diffusivity in the working memory training (WMT) group compared with the control group. Results are shown with a threshold of P < 0.05 and corrected for multiple comparisons at FDR within the regions of interest. Findings were overlaid on a “single-subject T1” SPM image. Bar represents the t score. The voxel-by-voxel analysis of covariance showed compared with the control intervention (no-intervention), WMT resulted in a significant increase in MD in nigrostriatal and mesocortical areas