Table 1.

Strengths and weaknesses of research techniques

Research technique	Strengths	Weaknesses
Tracing	High level of anatomical detail, information on connective properties	Usually low numbers of observations, highly dependent on injection site and volume
Cytoarchitectural approaches	High level of anatomical detail, information on chemical properties of cell populations	No information on connectivity, no functional data
Structural imaging	In vivo information	Low level of anatomical detail
Functional imaging	In vivo on distinct functions	Low level of anatomical detail
Clinical observations	Information on (dys)function	Low level of anatomical detail, usually low number of observations, not always normal brain function