Fig. 8.

Locomotion adaptation: number of steps, missteps and distribution of step sizes. Perturbed sessions are more challenging for mice than non-perturbed sessions. Consequently, throughout these sessions all cerebellar mutant mice showed impairments, some of which were not obvious during the non-perturbed sessions. a During perturbed sessions, all cerebellar mutant mice used significantly more steps to cross the ladder than control mice. b Likewise, all cerebellar mutant mice showed significantly more missteps. c Moreover, all cerebellar mutant mice also showed a significantly higher rate of small steps and a significantly lower rate of large steps. Error bars represent SEM. Significant differences between mutant and control mice are demonstrated with an asterisk