Table 2.

Behavior of cerebellar mutant mice during non-perturbed sessions

Locomotion performance												Interlimb coordination		Motivation
Mouse line	No. of steps	No. of missteps	Regular steps (%)		No. of blocks	Block size		Effc. trials (%)	Step time (ms)		CV2
			SL 2	SL 4		SL 2	SL 4		SL 2	SL 4		Front–hind	Left–right
Pcd	↑	↑	↑	↓	↑	n	↓	↓	n	↑	↑	imp.	imp.	n
L7-Pp2b	↑	n	↑	↓	n	n	↓	↓	↑	↑	n	imp.	imp.	n
L7-∆y2	↑	n	n	n	n	n	n	n	n	↑	n	imp.	imp.	n
α6-Cacna1a	n	n	n	n	n	n	n	n	n	n	n	imp.	imp.	n

During the non-perturbed sessions locomotion performance was severely impaired in Pcd and L7-Pp2 mice, but only slightly altered in L7-Δγ2 and α6-Cacna1a mice. At the same time, all four cerebellar mutant mouse lines exhibited poor interlimb coordination. None of the cerebellar mouse lines displayed deficits in motivation. Significant increases (↑) and decreases (↓) relative to control littermates are indicated; n indicates no significant difference found with repeated measures ANOVA

SL 2 step length = 2, SL 4 step length = 4, Effc. trials efficient trials, imp. impaired