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. 2014 Aug 20;220(6):3513–3536. doi: 10.1007/s00429-014-0870-1

Table 3.

Behavior of cerebellar mutant mice during perturbed sessions

Locomotion adaptation Interlimb coordination Avoidance behavior
Mouse line No. of steps No. of missteps Regular steps (%) No. of blocks Block size Effc. trials (%) Step time (ms) CV2
SL 2 SL 4 SL 2 SL 4 SL 2 SL 4 Front–hind Left–right
Pcd n imp. imp. n
L7-Pp2b n imp. imp. n
L7-∆y2 n n imp. imp. n
α6-Cacna1a n n n n imp. imp. n

During perturbed sessions locomotion adaptation and interlimb coordination were severely impaired in all four cerebellar mouse mutant lines. None of the cerebellar mouse lines displayed deficits in avoidance behavior. Significant increases (↑) and decreases (↓) relative to control littermates are indicated; n indicates no significant difference tested with repeated measures ANOVA

SL 2 step length = 2, SL 4 step length = 4, Effc. trials efficient trials, imp. impaired