. 2015 Sep 6;2015:648143. doi: 10.1155/2015/648143

Table 5.

Lack of immune reactivity of patient sera to plant glycans in idiotypic vaccines.

Patient UPIN¹	Predominant plant glycan type²	Vaccinated patient sera		Control⁴ glycosylated antibody pre	Control⁴ glycosylated antibody post
		Anti-HRP³	Anti-HRP³
		Pre-immune	Post-immune
U001	V: GnGnXF S: Gn(FA)XF; (FA)(FA)XF	0.076	0.068	0.071	0.065

T003	V: GnGnXF S: Gn(FA)XF; (FA)(FA)XF	0.081	0.103	0.084	0.080

T006	V: GnGnXF S: Gn(FA)XF	0.106	0.109	0.072	0.068

T008	V: GnGnXF	0.107	0.174	0.100	0.089

T010	V: MGnX S: GnAF/Gn(FA)	0.089	0.105	0.079	0.074

U011	V: GnGnXF S: Gn(FA)XF	0.078	0.069	0.156	0.130

U016	V: GnGnXF S: Gn(FA)XF	0.096	0.082	0.066	0.057

U017G	V: GnGnXF S: Gn(FA)XF	0.094	0.078	0.101	0.064

T021	V: GnGnXF	0.142	0.103	0.072	0.078

T022	V: GnGnXF	0.089	0.136	0.085	0.083

U026	V: GnGnXF S: GnA	0.067	0.069	0.062	0.066

Control anti-plant glycan antiserum (1 : 2000)		0.37		0.515

1 = UPIN: Unique Patient Identification Number (sera obtained from patients vaccinated as shown in Table 4).

2 = Predominant plant glycan type. V, vacuolar, with major species indicated; S, secretory, with major species indicated. A = galactose; Gn = N-acetyl glucosamine; M = mannose; F = fucose; X = xylose.

3 = HRP, horseradish peroxidase, a plant enzyme containing complex plant-type glycans used as a control.

4 = Irrelevant plant-produced glycosylated human idiotypic Ig used as a control.