. Author manuscript; available in PMC: 2016 Sep 1.

Published in final edited form as: J Cardiovasc Comput Tomogr. 2015 Mar 21;9(5):438–445. doi: 10.1016/j.jcct.2015.03.004

Table 3. Per-patient diagnostic performance of Combined Coronary CTA + myocardial CTP and coronary CTA alone for detection of flow-limiting stenosis^*.

	Overall		Previous CAD		No previous CAD

	CTA	CTA+CTP	CTA	CTA+CTP	CTA	CTA+CTP
Sensitivity, %	93 (88-97)	78^† (70-84)	89 (80-95)	71^† (60-80)	98 (91-100)	87^† (76-94)
Specificity, %	54 (47-60)	73^† (67-79)	27 (17-40)	57^† (44-70)	63 (56-70)	79^† (73-85)
PPV, %	55 (48-61)	64 (56-71)	61 (52-70)	68 (57-78)	49 (40-58)	60 (49-70)
NPV, %	93 (87-96)	85 (79-89)	65 (44-83)	60 (47-72)	99 (95-100)	95 (90-98)
Accuracy %	69 (64-73)	75^† (70-79)	62 (54-70)	65 (56-73)	72 (66-78)	81^† (76-86)

Gold-standard definition for disease is a ≥50% stenosis by QCA with related SPECT SSS (Summed Stress Score) ≥ 1 in one of the three vessels: LAD, LCX, or RCA.

^†

p<0.05 for difference from CTA alone by McNemar's test. Statistical comparisons of PPV and NPV were not performed.

CAD – Coronary Artery Disease; CTA – Computed Tomography Angiography; CTP – Computed Tomography Perfusion; PPV – Positive Predictive Value; NPV – Negative Predictive Value.

Table 3. Per-patient diagnostic performance of Combined Coronary CTA + myocardial CTP and coronary CTA alone for detection of flow-limiting stenosis*.

Table 3. Per-patient diagnostic performance of Combined Coronary CTA + myocardial CTP and coronary CTA alone for detection of flow-limiting stenosis^*.