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. Author manuscript; available in PMC: 2016 Oct 1.
Published in final edited form as: J Immunol. 2015 Aug 21;195(7):3284–3292. doi: 10.4049/jimmunol.1500683

Fig. 3. Macrophages lose capacity to induce IFN-γ production from allogeneic CD4 T cells in acute SIV infection.

Fig. 3

(A) A representative ELISPOT assay depicting T cells producing IFN-γ when co-cultured with isolated pDC, mDC, or macrophages isolated from naïve, acutely infected or chronically infected lymph nodes. Each co-culture is shown with and without exposure to Env976. Numbers represent the number of IFN-γ spot-forming units (SFU). (B) Quantification of IFN-γ SFU is shown per 1 million responder cells. Each symbol represents an individual animal. Repeated measures ANOVA and multiple comparisons tests were performed and each significant relationship is shown with capped bars. *P<0.05.