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. 2015 Sep 19;21:1101–1105.

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Copyright © 2015 Molecular Vision.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited, used for non-commercial purposes, and is not altered or transformed.

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The clinical retinal phenotype of two C3H congenic strains wild-type for Pde6b (used as the sighted control strains) and four C3H rd1 substrains. A: Normal fundus. B: Normal retinal structure by image-guided optical coherence tomography (OCT) at 6 weeks of age (representative strain is C3A.BLiA-Pde6b⁺/J). C: Retinal vessels are attenuated, and areas of retinal depigmentation are observed. D: Retinal degeneration with image-guided OCT at 6 weeks of age (the representative strain is C3H/HeJ). The green line across the fundus image indicates the location of the B-scan.