Supplementary Table 2. Stratified and interaction analysis between rs2853669 and smoking status associated with lung cancer risk.
| Genotype | Smoking status | |||||
|---|---|---|---|---|---|---|
| Nonsmokers | Smokers | |||||
| Cases/Controls | OR (95% CI)* | P | Cases/Controls | OR (95% CI)* | P | |
| TT + TC | 264/344 | Reference | 691/631 | 2.82 (2.02-3.94) | 1.1 × 10-9 | |
| CC | 47/40 | 1.49 (0.94-2.35) | 0.09 | 90/65 | 3.71 (2.35-5.86) | 1.9 × 10-8 |
| Pmult, Pmult† | 4.1 × 10-9, 2.4 × 10-8 | |||||
| Padd, Padd† | 0.02, 0.14 | |||||
*ORs and 95% CI were calculated by unconditional logistic regression after adjusting for sex and age; †P was modified by bonferroni correction for multiple comparisons. OR, odds ratio; CI, confidence interval; Pmult, P value for multiplicative interaction term; Padd, P value for additive interaction model.