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. 2015 Jul 29;114(3):1874–1884. doi: 10.1152/jn.00338.2015

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Fig. 10. — Analysis of the number of additional nodal sodium channels required to match the conduction velocity gains resulting from optimal nodal constrictions. A: the conduction velocity of a 20 μm fiber (12.9 μm internodal diameter) is plotted vs. the number of nodal sodium channels for an optimal (constricted) cable and an unconstricted (uniform) cable. For a specified conduction velocity (vertical axis), the horizontal distance between the two curves represents the number of additional sodium channels needed for the uniform cable. B: the necessary internodal diameter for a conduction speed of 25 m/s is shown as a function of the number of nodal sodium channels for the optimal cable and the uniform cable. For a specified internodal diameter (vertical axis), the horizontal distance between the curves represents the number of additional sodium channels needed for the uniform cable to conduct with the same speed of 25 m/s.