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Cross-resistance of doxorubicin-resistant cells to other chemotherapeutic agents.
| Agents | IC50 | P value | IC50 | P value | ||
|---|---|---|---|---|---|---|
| Jurkat | Doxorubicin-resistant Jurkat | H9 | Doxorubicin-resistant H9 | |||
| Cisplatin (uM) | 6.2 ± 0.3 | 9.0 ± 0.4 | 0.0039 | 5.7 ± 0.3 | 8.5 ± 0.5 | 0.0067 |
| Cyclophosphamide (mM) | 3.3 ± 0.2 | 4.8 ± 0.2 | 0.0056 | 2.4 ± 0.2 | 3.9 ± 0.3 | 0.0106 |
