Table 2.
Biochemical parameters in the study population.
| Variables | All patients (n = 419) | Diabetic patients with thyroid dysfunction (n = 151) | Diabetic patients without thyroid dysfunction (n = 268) | p value | |
|---|---|---|---|---|---|
| Hypothyroidism∗
(n = 134) |
Subclinical hyperthyroidism (n = 17) | ||||
| Fasting blood glucose (mg/dL) | 176.48 ± 57.53 | 174.13 ± 51.99 | 165.59 ± 53.25 | 178.35 ± 60.42 | 0.574 |
| HbA1c % | 7.21 ± 1.88 | 7.5 ± 2.13 | 6.73 ± 1.18 | 7.1 ± 1.77 | 0.076 |
| Total cholesterol (mg/dL) | 190.31 ± 53.08 | 191.05 ± 54.14 | 198.58 ± 46.13 | 189.41 ± 53.08 | 0.774 |
| HDL cholesterol (mg/dL) | 40.27 ± 3.6 | 40.72 ± 3.73 | 40.29 ± 3.01 | 40.05 ± 3.56 | 0.209 |
| LDL cholesterol (mg/dL) | 111.48 ± 44.9 | 112.09 ± 45.22 | 115.1 ± 45.21 | 110.95 ± 44.88 | 0.917 |
| Triglycerides (mg/dL) | 181.24 ± 103.61 | 178.72 ± 111.22 | 198.18 ± 99.52 | 181.42 ± 100.14 | 0.766 |
| Free T3 (pmol/L) | 5.03 ± 1.3 | 4.65 ± 1.21 | 5.63 ± 1.07 | 5.19 ± 1.31 | <0.001 |
| Free T4 (pmol/L) | 11.78 ± 3.52 | 10.45 ± 2.54 | 13.75 ± 3.48 | 12.31 ± 3.75 | <0.001 |
| TSH (mIU/L) | 4.62 ± 4.23 | 9.45 ± 4.31 | 0.18 ± 0.041 | 2.48 ± 1.12 | <0.001 |
The data is presented as mean ± SD. p value was calculated among diabetic subjects with hypothyroidism and hyperthyroidism and without thyroid dysfunction at 95% confidence interval. ∗Hypothyroidism group included both subclinical and overt hypothyroids.