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. 2015 Sep 7;2015:186586. doi: 10.1155/2015/186586

Table 3.

Library screening methods for cell SELEX.

Method Advantages Disadvantages
Panning High throughput, quick Less powerful separation, some undesired molecules remain after washes
Magnetic separation/MACS High throughput Limited space if using large cells (clogging), higher failure chance compared to panning with no advantages
FACS Very powerful separation ability with efficient tunability Lower throughput, slower processing, expensive equipment