FIG 2.
Genetic contexts of blaKPC-2 on pKPC1_ECl14653 and related plasmids. The plasmid names, host species (Ec, Ecl, and Kp stand for E. coli, E. cloacae, and K. pneumoniae, respectively) and locations of each structure are listed. The GenBank accession numbers are KP868647 for pKPC1_EC14653, CP006657 for plasmid p1 of K. pneumoniae strain JM45, KF826291 for pHS111288, KF826292 for pHS10505, KF623109 for pHS062105-3, FJ628167 for pKP048, KC405622 for pKPC-LK30, CP003224 for pKPHS2, KF724507 for pHS082416, and KF826293 for pHS092753. All of the plasmids were found in isolates from mainland China, except pKPC-LK30, which was from an isolate from Taiwan. The vertical lines are the IR of Tn3 (black) and Tn1722 (cyan). Open reading frames (ORFs) of unknown function are indicated by numbers 1 to 5.