TABLE 1.
Summary of demographics for subjects receiving tafenoquine and included in the logistic regression exposure-response analysis (6 months)
| Parameter | Means (SD) | Category | No. (%) |
|---|---|---|---|
| AUC (μg · h/ml) | 56.6a (46.8, 66.5) | ||
| Age (yr) | 35.7 (14.1) | ||
| Weight (kg) | 60.5 (12.0) | ||
| BMI (kg/m2) | 23.7 (4.52) | ||
| Status | Relapsed | 52 (32) | |
| Relapse free | 112 (68) | ||
| Gender | Male | 126 (77) | |
| Female | 38 (23) | ||
| Baseline parasitemia count | ≤7,500/μl | 117 (70) | |
| >7,500/μl | 47 (30) | ||
| Country | Brazil | 24 (15) | |
| Peru | 79 (48) | ||
| Thailand | 61 (37) | ||
| Dose | 50 mg | 40 (24.4) | |
| 100 mg | 43 (26.2) | ||
| 300 mg | 44 (26.8) | ||
| 600 mg | 37 (22.6) |
a
Data for AUC are geometric means and 95% CI on untransformed data.