TABLE 3.

Mutational analysis of CYP51A, CYP51B, and CYP51C and the corresponding amino acid changes in lanosterol 14 α-demethylase in resistant and sensitive isolates

Strain	Mutations in CYP51			Amino acid change in LDMa			Regulatory region of CYP51C
	CYP51A	CYP51B	CYP51C	CYP51A	CYP51B	CYP51C
NCCPF 761157	G680A	None	T161C	A205T	None	M54T	4-bp deletion at bp 2734
			T788G			S240A	at bp 2734
			G830A			D254N
			G923A			I285V
			T1025C			Y319H
NCCPF 760815	None	None	T161C	None	None	M54T	4-bp deletion at bp 2734
			T788G			S240A
			G830A			D254N
			G923A			I285V
NCCPF 760816	None	None	T161C	None	None	M54T	None
			T788G			S240A
NCCPF 760690	None	None	T161C	None	None	M54T	None
			T788G			S240A
NCCPF 761379	None	None	T161C	None	None	M54T	None
						S240A
NCCPF	None	None	T788G	None	None	M54T	None
761425						S240A

^aLDM, lanosterol 14 α-demethylase.