TABLE 3.
Phenotypic and genotypic results of resistant isolates of E. cloacaea
| Region | No. of isolates | β-Lactam resistance | ESBL gene(s) | Quinolone resistance | Quinolone gene | Aminoglycoside resistance | Aminoglycoside gene(s) |
|---|---|---|---|---|---|---|---|
| Algeria | 5 | CRO-CTX-CAZ-ATM-FEP | blaCTX-M15, blaTEM-1 | TOB-GAT | aadA2 | ||
| 3 | CRO-CTX-CAZ-ATM-FEP | blaCTX-M15, blaTEM-1 | CIP-OFX | qnrB42 | AMK-TOB | aac(6′)-Ib-cr | |
| 3 | CRO-CTX-CAZ-ATM-FEP | blaCTX-M15, blaTEM-1 | CIP-OFX | qnrB42 | AMK-TOB-GAT | aac(6′)-Ib-cr, aadA2, armA | |
| 1 | CRO-CTX-CAZ-ATM-FEP | blaCTX-M15, blaTEM-1 | CIP-OFX | qnrB1 | TOB-GAT | aadA2 | |
| 1 | CRO-CTX-CAZ-ATM-FEP | blaCTX-M15, blaTEM-1 | CIP-OFX | qnrB42 | AMK-TOB | aac(6′)-Ib-cr | |
| 1 | CRO-CTX-CAZ-ATM-FEP | blaCTX-M15 | TOB-GAT | aadA2 | |||
| 1 | CRO-CTX-CAZ-ATM-FEP | blaCTX-M15 | |||||
| 1 | CRO-CTX | blaCTX-M15 | CIP-OFX | AMK-TOB-GAT | aadA2, ant(2″)-Ia, aac(6′)-Ib-cr | ||
| 1 | CRO-CTX-CAZ-ATM-FEP | blaTEM-1 | TOB-GAT | aadA2 | |||
| 1 | CRO-CTX-CAZ-ATM | blaTEM-1 | TOB-GAT | aadA2 | |||
| 1 | CIP-OFX | qnrB42 | AMK-TOB | aac(6′)-Ib-cr | |||
| 2 | TOB-GAT | aadA2 | |||||
| Marseille | 2 | CRO-CTX-CAZ-ATM-FEP | blaCTX-M15, blaTEM-1 | TOB-GAT | aadA1 | ||
| 1 | CRO-CTX-CAZ-ATM-FEP | blaCTX-M15, blaTEM-1 | CIP-OFX | qnrB1 | TOB-GAT | ant(2″)-Ia | |
| 1 | CRO-CTX-CAZ-ATM-FEP | blaCTX-M15, blaTEM-1 | CIP-OFX | qnrA1 | TOB-GAT | ant(2″)-Ia | |
| 2 | CRO-CTX-CAZ-ATM-FEP | blaCTX-M15 | |||||
| 1 | CRO-CTX-CAZ-ATM-FEP | blaCTX-M15 | CIP-OFX | qnrB42 | TOB-GAT | aadA1 | |
| 1 | CRO-CTX-CAZ-ATM-FEP | blaCTX-M15 | CIP-OFX | qnrB42 | AMK-TOB-GAT | aac(6′)-Ib-cr, aadA1 | |
| 1 | CRO-CTX-CAZ-ATM-FEP | blaCTX-M15 | CIP-OFX | qnrA1 | TOB-GAT | ant(2″)-Ia | |
| 1 | CRO-CTX-CAZ-ATM-FEP | blaCTX-M15 | TOB-GAT | ant(2″)-Ia | |||
| 1 | CRO-CTX-CAZ-ATM-FEP | blaTEM-1 |
a
AMK, amikacin; ATM, aztreonam; CAZ, ceftazidime; CRO, ceftriaxone; CTX, cefotaxime; CIP, ciprofloxacin; FEP, cefepime; GAT, gentamicin; OFX, ofloxacin; TOB, tobramycin.