TABLE 1.
Baseline characteristics of isolates for which ex vivo assays were performed
| Baseline characteristic | Naphthoquine |
Methylene blue |
||
|---|---|---|---|---|
| P. falciparum (n = 25) | P. vivax (n = 38) | P. falciparum (n = 63) | P. vivax (n = 50) | |
| Isolates reaching harvest (no. [%]) | 21 (84.00) | 29 (76.32) | 52 (82.54) | 41 (82.00) |
| Delay from venepuncture to start of culture (median [range]) (min) | 160 (85–310) | 178 (55–330) | 125 (60–310) | 148 (55–330) |
| Duration of assay (median [range]) (h) | 44 (32–48) | 47 (42–50) | 45 (32–50) | 46 (32–50) |
| Parasitemia (geometric mean [95% CIa]) (asexual parasites/μl) | 24,102 | 25,001 | 13,343 | 22,454 |
| (15,856–36,637) | (17,487–35,742) | (11,059–16,099) | (16,531–30,501) | |
| Parasites at ring stage initially (median [range]) (%) | 100b | 96 (71–99) | 100b | 96 (70–99) |
| Schizont count at harvest (mean [range]) (%) | 50 (16–76) | 45 (13–70) | 42 (14–75) | 43 (13–70) |
a
CI, confidence interval.
b
No range given (all values were 100%).