Skip to main content
. 2015 Aug 13;109(6):1227–1239. doi: 10.1016/j.bpj.2015.06.044

Figure 1.

Figure 1

The interaction of GR with the components of the SWI/SNF-A (BAF) complex. SWI/SNF complexes consist of a single ATPase (BRM or BRG1, red), evolutionarily conserved core proteins (BAF155, BAF170, and BAF47, purple), and variant subunits (BAF60a, b, or c; BAF57; BAF53a or b; BAF250a or b; and β-actin, green). Pull-down experiments indicate that there are at least three proteins in the BAF complex that can associate with GR (orange). The dashed lines represent the hinge region (40 residues long) between the DBD and LBD of GR. BAF250 binds to the GR LBD, and BAF57 and BAF60 bind to the GR DBD. To see this figure in color, go online.