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Establishing cytokine signature of CD4 cells. PBMC from 45 healthy donors were tested for HCMV-induced cytokine production of IFN-γ, IL-2, IL-4, and IL-17. (A) The percentage of donors that generated a recall response to the HCMV antigen for each of the cytokines is shown. (B) The percentage of individual donors representing the various CD4 effector lineages is shown.
