Table 1.
Results of cardiovascular reflex tests and 24-h heart rate variability (HRV) parameters in patients with PBC and age matched healthy controls
| Patients with PBC (n = 24) | Age-matched controls (n = 20) | P value | |
| Cardiovascular reflex tests | |||
| Deep breathing test (beats/min) | 11.3 (4.4) | 17.5 (6.6) | 0.001 |
| 30/15 ratio | 1.18 (0.1) | 1.29 (0.2) | 0.03 |
| Valsalva ratio | 1.32 (0.1) | 1.48 (0.2) | 0.01 |
| Orthostatic test (mmHg) | -7.1 (8.6) | -1.5 (3.7) | 0.03 |
| Handgrip test (mmHg) | 20.4 (8.1) | 22.3 (4.4) | NS |
| Time domain parameters of HRV | |||
| SDNN (ms) | 119 (42) | 151 (37) | 0.015 |
| SDANN (ms) | 142 (102) | 165 (66) | NS |
| RMSSD (ms) | 23 (10) | 38 (22) | 0.006 |
| PNN50 (%) | 2.4 (4) | 11 (10) | 0.0008 |
| HRVTI | 28 (8) | 38 (13) | 0.004 |
| Frequency domain parameters of HRV | |||
| TP (ms²) | 1506 (701) | 3.61 (2787) | 0.0001 |
| LF (ms²) | 299 (176) | 1.40 (977) | 0.00007 |
| HF (ms²) | 150 (148) | 1.06 (565) | 0.004 |