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. 2015 Oct 1;38(10):1537–1546. doi: 10.5665/sleep.5042

Figure 3.

Figure 3

Inflammatory cytokine messenger RNA (mRNA) in the dorsal hippocampus after chronic intermittent hypoxia and chronic low-dose lipopolysaccharide. (A) RANTES/CCL5, ICAM-1, TNF-α, IL1-β, MCP-1/CCL2 and (B) IL-6 and IL-10 mRNA in the dorsal hippocampus after 6 w intermittent hypoxia (IH) or normoxia (N) associated for the past 3 w with repeated intraperitoneal low-dose lipopolysaccharide (LPS) or saline (NaCl). Levels of mRNA were normalized to the RPLP0, ACTB, and HPRT1 genes, and are shown as a ratio to the level found in control animals exposed to 6 w of N and receiving NaCl instead of LPS. Results are expressed as mean ± standard error of the mean (n = 5 for each group, *P < 0.05, **P < 0.01 and ***P < 0.001 versus N group, #P < 0.05 and ##P < 0.01 versus N/LPS).