Table 2.
Pretreatment Laboratory Values for Patients With and Without Chemotherapy-Related Hospitalizationa
| Laboratory Variable | Cases (n = 146) |
Controls (n = 292) |
OR (95% CI)b | P Value |
|---|---|---|---|---|
| White blood cell count, ×1000/µL | ||||
| ≥3.8 | 134 (92) | 283 (97) | 1 [Reference] | .02 |
| <3.8 | 12 (8) | 9 (3) | 2.82 (1.16–6.85) | |
| Absolute neutrophil count, ×1000/µL | ||||
| ≥1.8 | 141 (97) | 286 (98) | 1 [Reference] | .26 |
| <1.8 | 5 (3) | 5 (2) | 2.03 (0.58–7.12) | |
| Hemoglobin, g/dL | ||||
| ≥12 | 75 (51) | 181 (62) | 1 [Reference] | .03 |
| <12 | 71 (49) | 111 (38) | 1.54 (1.03–2.31) | |
| Platelet count,, ×1000/µL | ||||
| ≥150 | 127 (87) | 277 (95) | 1 [Reference] | .004 |
| <150 | 19 (13) | 15 (5) | 2.76 (1.36–5.61) | |
| Aspartate aminotransferase, IU/L | ||||
| ≤46 | 119 (82) | 260 (89) | 1 [Reference] | .03 |
| >46 | 26 (18) | 31 (11) | 1.83 (1.04–3.22) | |
| Alkaline phosphatase, IU/L | ||||
| ≤118 | 106 (73) | 216 (74) | 1 [Reference] | .80 |
| >118 | 39 (27) | 75 (26) | 1.06 (0.68–1.66) | |
| Lactate dehydrogenase, IU/L | ||||
| ≤250 | 107 (75) | 228 (84) | 1 [Reference] | .05 |
| >250 | 35 (25) | 45 (16) | 1.66 (1.01–2.73) | |
| Creatinine clearancec | ||||
| 10 mL/min increase | NA | NA | 0.93 (0.87–0.99) | .03 |
| Albumin | ||||
| 1 g/dL increase | NA | NA | 0.61 (0.42–0.89) | .01 |
| Calcium | ||||
| 1 mg/dL increase | NA | NA | 0.51 (0.34–0.77) | .001 |
Abbreviations: NA, not applicable; OR, odds ratio.
a
Unless otherwise noted, data are number (percentage) of patients.
b
Univariate analysis.
c
Creatinine clearance was estimated by the Cockcroft-Gault equation; values were capped at a maximum of 120 mL/min.