. Author manuscript; available in PMC: 2016 Jul 1.

Published in final edited form as: JAMA Oncol. 2015 Jul 1;1(4):441–447. doi: 10.1001/jamaoncol.2015.0828

Table 3.

Multivariable Regression Model to Predict Chemotherapy-Related Hospitalization

Variable	OR (95% CI)^a	P Value
Age, 1-y increase	0.96 (0.94–0.98)	<.001
Creatinine clearance, 10 mL/min increase	0.87 (0.82–0.93)	<.001
Calcium, 1 mg/dL increase	0.47 (0.33–0.67)	<.001
Low platelet and/or WBC count^b	5.02 (2.25–11.24)	<.001
CCS
0	1 [Reference]	NA
1	2.79 (1.63–4.75)	<.001
≥2	3.67 (2.23–6.03)	<.001
Polychemotherapy	1.80 (1.21–2.66)	.003
Camptothecin chemotherapy	2.02 (1.14–3.57)	.02
Interaction terms
Low platelet and/or WBC count × CCS 1	0.15 (0.03–0.71)	.02
Low platelet and/or WBC count × CCS ≥2	0.48 (0.16–1.39)	.18

Abbreviations: CCS, Charlson comorbidity score; NA, not applicable; OR, odds ratio; WBC, white blood cell.

ORs are not directly interpretable for variables with interaction terms.

Platelet count lower than 150 000/µL and/or WBC count lower than 3800/µL.