Table 2.

Summary of significant group EC differences related to penetration of DBS electrodes in the STN (i.e., contrast = post-implantation − pre-implantation).

Structure	PFDR‡	k	punc	t	x	y	z
Upper brainstem	0.041	62
Maximum 1			2.7·10−5	6.10	−3	−28	−17
Maximum 2			0.002	3.45	−15	−31	−17
Lower brainstem (left)	0.019	88
Maximum 1			8.1·10−5	5.39	−12	−37	−41
Maximum 2			5.1·10−4	4.31	−9	−43	−50
Maximum 3			0.002	3.52	−18	−43	−50
Lower brainstem (right)	0.475a	21
Maximum 1			2.0·10−4	4.84	9	−34	−41
Maximum 2			4.5·10−4	4.38	15	−37	−50

Bold typeface letters denote obtained clusters and associated statistics at the cluster-level, while nested standard typeface letters are related to statistical values of the local maxima (at the voxel-level) identified within the respective cluster. DBS — deep-brain stimulation; EC — eigenvector centrality; k — number of significant voxels within the cluster; MNI — Montreal Neurological Institute; p_FDR‡ — alpha value corrected for multiple tests at cluster-level using false discovery rate correction; p_unc — uncorrected alpha value; STN — subthalamic nucleus; t — peak t-statistic; [x, y, z] — coordinates of corresponding voxel in MNI-template anatomical space in millimeters;

^aThe right brainstem cluster did not survive the FDR cluster-level correction.