Table 1.
Clinical Effects of Ketamine on Neuropsychological Parameters
| Test | Placebo Scan | Ketamine Scan | P |
|---|---|---|---|
| PANSS | |||
| Positive scale | 7.2±0.4 | 14.5±4.7 | <.001 |
| Negative scale | 7.3±1.0 | 9.2±2.9 | .002 |
| General scale | 16.6±1.5 | 30.4±8.9 | <.001 |
| Overall score | 31.1±2.4 | 54.1±14.6 | <.001 |
| 5D-ASC | |||
| Oceanic boundlessness | 1.45±3.3 | 84.26±57.9 | <.001 |
| Anxious ego-dissolution | 3.08±5.6 | 40±34.83 | <.001 |
| Visual reconstruction | 0.6±2.5 | 44.9±33.9 | <.001 |
| Auditory alterations | 1.63±4.3 | 21.72±18,8 | <.001 |
| Vigilance reduction | 8.75±12.8 | 40.33±25.15 | <.001 |
Abbreviations: 5D-ASC, Altered State of Consciousness Scale, PANSS, Positive and Negative Syndrome Scale.
P-values derived from a paired t test; mean values are indicated±SD; n=30.