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Summary of membrane-based and cell-based assays to evaluate Parkinson’s disease–associated pesticides as P-gp substrates and inhibitors
| Membrane-Based Assay |
Cell-Based Assay |
||
|---|---|---|---|
| ATPase | Cytotoxicity | R123 Inhibition | |
| Diazinon | ✔ | — | — |
| Dieldrin | — | — | — |
| Endosulfan | — | — | — |
| Maneb | — | — | — |
| MPP+ | — | ✔ | — |
| Rotenone | ✔ | ✔ | — |
