Fig. 6.

Enrichment of SDV for biologically relevant GO categories. (A) Selected set of 1,634 SDV is enriched for genes in several GO categories. On the x axis are number of genes with at least one SDV in each category and y axis indicates significance of enrichment after correcting for multiple testing. Dotted purple line indicates FDR <5%. Each dot is a GO category and size of the dots indicates the total number of genes in each GO category. Dots in gray: Broad GO categories containing several specialized GO terms; dots in blue, red, and orange: GO categories associated with reproduction (and egg development), growth, and cell size, respectively. (B) Overlap of genes harboring the enriched SDV in GO categories associated with cell size, egg development, and growth. Genes in differentiated blocks are largely distinct from those encompassed by the differentiated blocks. All of the genes in the differentiated blocks are expressed in the Drosophila ovaries (fig. 5B).